In respiratory diseases such as asthma, emphysema and COPD, ozone provides adaptation to the oxidative stress that occurs. The main problems in the treatment of bronchial asthma are control of infections, strengthening of the immune system, bronchial obstruction, allergic reactions and oxygen deficiency.

Obstructive pulmonary disorders frequently involve pulmonary hypertension as well. Patients with asthma who have trouble breathing have issues with their blood's oxygen saturation level dropping and carbon dioxide level rising. Through the removal of pathogenic pathogens, boosting of the immune system, and high-energy oxygenation of the blood, ozone is curative in these patients. These individuals feel relaxed thanks to the vasodilator effects of ozone. The blood's ability to carry oxygen rises, eradicating the hypoxia that develops in the tissues.

As a result of the effect of ozone on endothelial cells, bronchial spasm is resolved by the relaxation of smooth muscles. This leads to relaxation of breathing. Chronic Bronchitis is one of the most common respiratory diseases. The local and general defense power, which is decreased in this disease, is strengthened by ozone therapy. As a result of the increase in T lymphocytes and T helper cells, Ig A and IG M immunoglobulins in the serum also increase.

Immune complexes increase in circulation and phagocyte neutrophils are activated. Inflammation of the bronchi is reduced. These cause relaxation of breathing and a decrease in the amount of secretion (sputum). As a result of Antalya Ozone treatment, these patients' complaints of suffocation and difficulty in breathing quickly improve. On the other hand, the dose of the drugs they normally have to use decreases. Scientific studies have shown that the drug doses used in 65% of asthmatic patients are reduced by more than 50%.