Glutathione is a molecule found in every cell of the body and is known as an antioxidant. Antioxidants are substances that combat free radicals in the body, reducing oxidative stress. While most antioxidants are found in the food you eat, glutathione is produced by your body.
Glutathione is composed of three different amino acids: glutamine, cysteine, and glycine. Glutathione has high metabolic activity, and various factors can cause a decrease in the body's glutathione levels, including poor nutrition, chronic illness, infection, and constant stress. Similar to collagen protein, glutathione is also a type of antioxidant that diminishes in production as the body ages. Maintaining adequate levels of this antioxidant is incredibly important. Glutathione levels can be increased through foods containing glutathione or oral glutathione supplements.
Benefits of Glutathione:
Antioxidant Activity:
Free radicals can contribute to aging and certain diseases. Antioxidants help counteract free radicals and protect the body from their harmful effects. Glutathione is a potent antioxidant found in high concentrations in nearly every cell in the body.
Prevention of Cancer Progression:
Some research suggests that glutathione may play a role in preventing the progression of cancer. However, the same research indicates that glutathione may make tumors less responsive to chemotherapy, a common cancer treatment. Further research is needed to determine the effects of glutathione on cancer.
Reduction of Cell Damage in Liver Disease:
Conditions such as hepatitis, alcohol misuse, and fatty liver disease can damage liver cells. A small 2017 clinical study suggested that glutathione, due to its antioxidant properties, could help with non-alcoholic fatty liver disease and have detoxification potential. Researchers emphasize the need for larger studies to confirm this effect.
Increased Insulin Sensitivity:
Insulin resistance can lead to the development of type 2 diabetes. A small 2018 study indicated that individuals with complications related to insulin resistance tended to have lower glutathione levels, potentially contributing to neuropathy or retinopathy. A similar conclusion was reached in a 2013 study.
Reduced Symptoms of Parkinson's Disease:
Some research suggests that maintaining glutathione levels may help alleviate symptoms of Parkinson's disease. Findings support the use of injected glutathione as a potential treatment, but there is limited evidence regarding oral supplementation, necessitating further research.
Mitigation of Ulcerative Colitis Damage:
Like other inflammatory diseases, ulcerative colitis is associated with oxidative damage and stress. Determining the effects of glutathione on ulcerative colitis will require further research in humans.
Treatment of Autism Spectrum Disorders:
There is evidence indicating that children with autism spectrum disorders have lower glutathione levels than neurotypical children. In 2011, researchers found that oral or injected glutathione supplements might reduce some effects of autism. However, further research is needed to determine whether any improvement occurs.
Conclusion:
Glutathione therapy offers a range of potential benefits, from antioxidant protection and cancer prevention to liver health and insulin sensitivity. While more research is needed to fully understand the extent of its effects in various conditions, maintaining optimal glutathione levels appears to be crucial for overall health and well-being.
